Gynaecological Trials

Trial Title Who can participate? Where is the trial open? What question is the trial asking? Full trial information
CTRIAL 25-63 Micro-GI Feasibility:

A randomised controlled feasibility study assessing the feasibility of a probiotic-use and dietary counselling intervention for endometrial cancer patients receiving pelvic radiation therapy.

People with endometrial cancer who are planned to receive external-beam radiotherapy as part of their cancer treatment.

  • St. Luke’s Hospital, Rathgar
  • St. Luke’s Centre @ Beaumont Hospital
  • St. Luke’s Centre @ St. James’s Hospital


This study is looking at whether probiotics (helpful bacteria) and specific dietary advice can help reduce side effects to the gut (bowel) that are sometimes caused by radiotherapy.

To test this, patients will be randomly divided into two groups:

One group will receive probiotic sachets and extra dietary advice about using probiotics.

The other group will receive the standard care that patients normally get during radiotherapy.

This study is currently at feasibility phase so we are investigating whether it is possible to collect the data which would be required to answer this question.
Trial information:
CTRIAL 25-64 SPAREKID:

Multi-markers risk assessment of kidney sensitivity to injury to personalize prevention of acute kidney injury – Cancer Chemotherapy

All patients planned to receive the following chemotherapy drugs: cisplatin, methotrexate, carboplatin or oxaliplatin. Patients with end-stage kidney disease or patient who are on dialysis cannot take part.
  • St. Luke’s Hospital

 

The main goal of the study is to find out how accurate a new kidney injury (AKI) biomarker test is at predicting kidney problems after the first cycle of cancer chemotherapy.
If the test can accurately predict kidney issues early, doctors may be able to change or adjust cancer treatment before serious kidney damage happens, helping protect kidney function and improve patient safety.
This is an observational study, which means it will not change or interfere with your treatment in any way.

All that’s required is that a small amount of extra blood is collected at the same time you’re already having blood tests, and that urine samples are also provided at those times.

All other information needed for the study will be taken from your medical records, so no additional appointments or procedures are needed.
Trial Information